I don’t notice it often, but I keep my laptop plugged in and on for longer and longer nowadays. And except for Firefox (which I ditch and switch back every two weeks) everything else swims along fine.
[vishnu@Elena:~]$ uptime 23:16 up 10 days, 22:21, 6 users, load averages: 0.05 0.10 0.13
What’s yours? 😉